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CoQ10 Usually Unnecessary, but Cardiologist Describes Its Use for Some Statin Patients

USA Today reported that most people do not need CoQ10 supplements, while evidence for treating several conditions remains mixed.

By Evoke Media Analysis1 min readShareXFacebookLinkedIn

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Illustration of an unlabelled white supplement bottle beside golden softgel capsules on a sunlit wooden table.
Illustration of an unlabelled white supplement bottle beside golden softgel capsules on a sunlit wooden table.Illustration: Evoke Media

Most people do not need supplemental CoQ10 because their cells already manufacture it, USA Today reported, citing Dr. Albert Raizner, a cardiologist at Houston Methodist Hospital.

Coenzyme Q10 is a naturally occurring antioxidant that helps cells generate energy and protects against cell damage. According to USA Today, it is found throughout the body, particularly in energy-intensive organs and tissues including the heart, kidneys, liver and muscles.

Raizner told the outlet that statins can reduce cellular CoQ10 levels and that lower levels also occur in some patients with heart failure. In clinical practice, he said, supplements are often recommended for statin users experiencing associated muscle aches, cramps or weakness.

That use does not amount to approval as a disease treatment. USA Today reported that CoQ10 is regulated as a dietary supplement and has no Food and Drug Administration approval for a specific clinical indication. Manufacturers cannot claim their supplements treat, cure or prevent particular diseases.

One clinical study found benefits for patients with milder congestive heart failure, according to USA Today, but heart failure specialists have not widely accepted the treatment. Results involving migraine, Parkinson’s disease and diabetes have been mixed or inconclusive.

Raizner also described infrequent, generally mild side effects, including reduced appetite, sleep disturbances, gastrointestinal symptoms, headaches, dizziness, itching and elevated liver function tests, USA Today reported.

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